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Statistic
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Details for phenotype: positive regulation of leukocyte migration
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EndoNet ID: ENP00247
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Name
positive regulation of leukocyte migration
General information
This phenotype is not pathologic
Links to other resources
GO
positive regulation of leukocyte migration
MeSH term
68002465
Phenotype triggers
normal activity of
Sphingosine 1-phosphate receptor 5
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in
killer_cell
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NK cells rely on S1PR5 to attain a normal tissue distribution, which might also function to promote egress from the bone marrow and lymph nodes into the vascular compartments in response to S1P gradients.
[1]
normal activity of
Sphingosine 1-phosphate receptor 4
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in
T-lymphocyte
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S1P has been reported to stimulate migration of T cells that express s1p4 under some conditions. T cell receptor-mediated activation of T cells suppresses expression of s1p4, and it has been reported to eliminate their migration responses to S1P.
[2]
normal activity of
Sphingosine 1-phosphate receptor 1
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in
T-lymphocyte
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S1P has been reported to stimulate migration of T cells that express s1p1 under some conditions. T cell receptor-mediated activation of T cells suppresses expression of s1p1, and it has been reported to eliminate their migration responses to S1P.
[2]
Reference