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Details for phenotype: skeletal system development

EndoNet ID: ENP00276

Name

skeletal system development

General information

This phenotype is not pathologic

Links to other resources

GO
MeSH term 68012863

Phenotype triggers

  • normal activity of Lysophosphatidic acid receptor 1
    in osteoblast
    • The finding of craniofacial deformities in mice in which the gene for edg-2 has been deleted suggests that phospholipids may participate in skeletal development. [1]
  • RAR
    in chondrocyte
    • The results of our study demonstrate for the first time that chondrocyte maturation in the cartilaginous skeletal elements of chick embryo limbs involves marked changes in RAR gene expression [2]
Reference