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Statistic
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Details for phenotype: negative regulation of neuron projection development
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EndoNet ID: ENP00339
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Name
negative regulation of neuron projection development
General information
This phenotype is not pathologic
Links to other resources
GO
negative regulation of neuron projection development
MeSH term
68016501
Phenotype triggers
more activity (high ligand concentration, overexpression) of
Lysophosphatidic acid receptor 1
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in
neuron
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Overexpression of LPA1 results in neurite retraction and cell rounding when stimulated with LPA
[1]
more activity (high ligand concentration, overexpression) of
Lysophosphatidic acid receptor 2
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in
neuron
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Overexpression of LPA2 results in neurite retraction and cell rounding when stimulated with LPA.
[1]
normal activity of
Sphingosine 1-phosphate receptor 2
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in
neuron
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S1PR2 is a cell surface receptor responsible for cell rounding and neurite retraction induced by S1P.
[2]
Reference
