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Statistic
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Details for phenotype: neuron projection morphogenesis
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EndoNet ID: ENP00340
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Name
neuron projection morphogenesis
General information
This phenotype is not pathologic
Links to other resources
GO
neuron projection morphogenesis
MeSH term
68016501
Phenotype triggers
more activity (high ligand concentration, overexpression) of
Lysophosphatidic acid receptor 3
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in
neuron
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Overexpression of LPA3 in neuroblastoma cells leads to neurite elongation.
[1]
normal activity of
Sphingosine 1-phosphate receptor 2
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in
brain
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In neuronal cell culture, SP1 acts through S1P2 and S1P5 to regulate neurite retraction and soma rounding.
[2]
Reference
