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Statistic
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Details for phenotype: lymphocyte homeostasis
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EndoNet ID: ENP00343
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Name
lymphocyte homeostasis
General information
This phenotype is not pathologic
Links to other resources
GO
lymphocyte homeostasis
MeSH term
68055635
Phenotype triggers
normal activity of
Probable G-protein coupled receptor 132
ui-button
in
lymphocyte
ui-button
Old G2A-deficient mice (older than 1 year) develop a late-onset autoimmune syndrome, indicating that G2A plays a role in the control of lymphocyte homeostasis.
[1]
normal activity of
Probable G-protein coupled receptor 132
ui-button
in
spleen
ui-button
Disruption of G2A in mice leads to immunological disorders. The G2A(-/-) mice develop enlarged spleens with abnormal expansion of both T- and B-lymphocytes.
[1]
normal activity of
Probable G-protein coupled receptor 132
ui-button
in
lymph_node
ui-button
Disruption of G2A in mice leads to immunological disorders. The G2A(-/-) mice develop enlarged lymph nodes with abnormal expansion of both T- and B-lymphocytes.
[1]
Reference