Details for phenotype: modulation of T cell response

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EndoNet ID: ENP00368

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Name

modulation of T cell response

General information

This phenotype is not pathologic

Links to other resources

GO	T cell homeostasis

Phenotype triggers

• normal activity of Probable G-protein coupled receptor 132 ui-button
  in T-lymphocyte ui-button
  • Genetic ablation of G2A function in mice has revealed a role for G2A in the homeostatic regulation of lymphocyte pools and the maintenance of immunological tolerance. G2A-deficient mice T lymphocytes exhibit hyperproliferative responses to antigen receptor stimulation. [1]

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