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Statistic
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Details for phenotype: negative regulation of catecholamine biosynthetic process
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EndoNet ID: ENP00396
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Name
negative regulation of catecholamine biosynthetic process
General information
This phenotype is not pathologic
Links to other resources
GO
catecholamine biosynthetic process
MeSH term
68002395
Phenotype triggers
normal activity of
BMP receptor type II
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in
adrenal_medulla
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BMPs have the potential to influence aldosterone-dependent dopamine production.
[1]
BMPs are thought to influence catecholamine production of adrenomedullary cells via an indirect mechanism through interfering with steroid hormone-dependent signalling pathways.
[2]
BMPs can inhibit dopamine expression and reduced DOPA decarboxylase mRNA expression in a dose-dependent manner, thereby acting antagonistic to glucocorticoids.
[2]
Reference
