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Details for phenotype: negative regulation of adrenocorticotropin receptor activity

EndoNet ID: ENP00399

Name

negative regulation of adrenocorticotropin receptor activity

General information

This phenotype is not pathologic

Links to other resources

GO
MeSH term 68044103

Phenotype triggers

  • normal activity of BMP receptor type II
    in adrenal_cortex
    • Expression levels of several steroidogenic enzymes, catalyzing the different steps of hormone production, as well as the ACTH receptor (melanocortin 2 receptor), were also inhibited by BMP-2 and BMP-5 treatment in a dose- and time-dependent manner. [1]
Reference