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Details for phenotype: mediation of effects from thymus on liver

EndoNet ID: ENP00420

Name

mediation of effects from thymus on liver

General information

This phenotype is not pathologic

Links to other resources

GO
MeSH term 68013950

Phenotype triggers

  • normal activity of AR
    in liver
    • The thymus plays an important role in maintaining the drug-metabolizing enzyme activity, anti-oxidative ability and biomembrane integrity in the liver of rats. These effects are mediated by sex hormones. Androgen mainly mediates the regulation of the thymus on liver drug-metabolizing enzymes in male rats. [1]
  • normal activity of ER-alpha
    in liver
    • The thymus plays an important role in maintaining the drug-metabolizing enzyme activity, anti-oxidative ability and biomembrane integrity in the liver of rats. These effects are mediated by sex hormones. Estrogen mainly mediates the effect of the thymus on liver anti-oxidative functions in female rats. [1]
  • normal activity of ER-beta
    in liver
    • The thymus plays an important role in maintaining the drug-metabolizing enzyme activity, anti-oxidative ability and biomembrane integrity in the liver of rats. These effects are mediated by sex hormones. Estrogen mainly mediates the effect of the thymus on liver anti-oxidative functions in female rats. [1]
Reference