Details for phenotype: negative regulation of lymphocyte apoptosis

EndoNet ID: ENP00431

Name

negative regulation of lymphocyte apoptosis

This phenotype is not pathologic

GO	negative regulation of lymphocyte apoptosis
MeSH term	68055635

normal activity of PRLR
in lymphocyte
- In addition to stimulating proliferation, PRL has been shown to inhibit apoptosis of lymphocytes. [1]
normal activity of TNFRSF18 isoform 1
in spleen
- TNFRSF18 and its ligand may modulate T lymphocyte survival in peripheral tissues and perhaps during interaction with the vascular endothelium. [2]
normal activity of TNFRSF17
in B-lymphocyte
- TNFRSF17 is a functional member of the TNFR superfamily. It is lacking a "death domain" and its overexpression activates NF-{kappa}B, p38, and JNK. Therefore, upon binding of its corresponding ligand, TNFRSF17 transduces signals for cell survival and proliferation. [3]
normal activity of TNFRSF13C
in lymph_node
- TNFRSF13C has a important role in mediating normal immune function. [4]
- Mice expressing a mutant form of this receptor show severe defects in B-cell development and survival and in T lymphocate-dependent immune respose. [5]
normal activity of TNFRSF13C
in spleen
- TNFRSF13C has a important role in mediating normal immune function. [4]
- Mice expressing a mutant form of this receptor show severe defects in B-cell development and survival and in T lymphocate-dependent immune respose. [5]
normal activity of TNFRSF13C
in thymus
- TNFRSF13C has a important role in mediating normal immune function. [4]
- Mice expressing a mutant form of this receptor show severe defects in B-cell development and survival and in T lymphocate-dependent immune respose. [5]

Reference