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Details for phenotype: polyhydramnios
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EndoNet ID: ENP00442
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Name
polyhydramnios
General information
This phenotype is pathologic
Polyhydramnios describes an excess of amniotic fluid in the amniotic sac.
[1]
Links to other resources
GO
water homeostasis
Medline Plus
003267
MeSH term
D006831
Disease database
10319
Phenotype triggers
PRLR
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in
chorion
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An excessive volume of amniotic fluid, known as polyhydramnios, is associated with decreased levels of amniotic fluid PRL or PRLR levels in the chorion laeve.
[2]
This effect may be related to the osmoregulatory role of PRL during fetal life and to the inhibitory effect on amniotic fluid volume observed in monkeys.
[3]
Reference
