Details for phenotype: Diabetes mellitus type 2

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EndoNet ID: ENP00454

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Name

Diabetes mellitus type 2

General information

This phenotype is pathologic

• Diabetes is a metabolic disorder, the primary manifestation of which is elevated circulating blood glucose levels. [1]

Links to other resources

GO	response to insulin stimulus
Medline Plus	000313
MeSH term	D003924
Disease database	3661

Phenotype triggers

• insulin receptor ui-button
  in beta_cell_of_islet_of_Langerhans ui-button
  • Diabetes is a metabolic disorder, the primary manifestation of which is elevated circulating blood glucose levels. [1]
  • Mutations in the insulin receptor can lead to severe insulin resistance. [2]
  • Insulin resistance can occur due to downregulation of insulin receptors. [3]

EndoNet at the Institut for Bioinformatics UMG Göttingen