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Statistic
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Details for phenotype: Diabetes mellitus type 1
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EndoNet ID: ENP00484
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Name
Diabetes mellitus type 1
General information
This phenotype is pathologic
Diabetes mellitus is a disorder of the metabolic homeostasis controlled by insulin, resulting in abnormalities of carbohydrate and lipid metabolism.
[1]
Links to other resources
GO
regulation of insulin secretion
OMIM
222100
Medline Plus
000305
MeSH term
D003922
Disease database
3649
Phenotype triggers
no activity (knock out experiment or RNAi) of
insulin receptor
ui-button
in
beta_cell_of_islet_of_Langerhans
ui-button
Type 1 diabetes (also called juvenile-onset diabetes mellitus and insulin-dependent diabetes mellitus) is caused by an absolute insulin deficiency, the result of a loss of the insulin-producing beta cells of the pancreas.
[1]
Reference
