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The information resource about the endocrine network in human.
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Details for phenotype: Glucagonoma
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EndoNet ID: ENP00489
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Name
Glucagonoma
General information
This phenotype is pathologic
Glucagonoma of the pancreas is a rare tumor with distinct clinical manifestations, such as necrolytic migratory erythema,weight loss, anemia, diabetes mellitus, and hypoamino-acidemia.
[1]
Links to other resources
GO
regulation of glucagon secretion
MeSH term
D005935
Disease database
5257
Phenotype triggers
more activity (high ligand concentration, overexpression) of
GL-R
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in
pancreas
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Glucagonoma is a tumor of the alpha cells of the pancreas that results in an overproduction of the hormone glucagon. Alpha cell tumors are commonly associated with glucagonoma syndrome.
[2]
Reference