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Details for phenotype: Secondary hyperparathyroidism
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EndoNet ID: ENP00497
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Name
Secondary hyperparathyroidism
General information
This phenotype is pathologic
Secondary hyperparathyroidism develops as a result of impaired calcium homeostasis when the failing kidneys disturb the complicated interactions between parathyroid hormone, calcium, phosphorus, and vitamin D.
[1]
Links to other resources
GO
response to parathyroid hormone stimulus
MeSH term
D006962
Disease database
6301
Phenotype triggers
VDR
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in
kidney
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Chronic renal failure is the most common cause of secondary hyperparathyroidism. Failing kidneys do not convert enough vitamin D to its active form, and they do not adequately excrete phosphorus.
[1]
Reference
