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Details for phenotype: Hyperprolactinemia
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EndoNet ID: ENP00506
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Name
Hyperprolactinemia
General information
This phenotype is pathologic
Hyperprolactinemia is a condition of elevated serum prolactin. Any process interfering with dopamine synthesis, its transport to the pituitary gland, or its action at the level of lactotroph dopamine receptors can cause hyperprolactinemia.
[1]
Links to other resources
GO
prolactin secretion
MeSH term
D006966
Disease database
6314
Phenotype triggers
dopamine receptor D2
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acidophil_mammotroph_cell_of_anterior_pituitary
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Hyperprolactinaemia is common in patients with hypopituitarism, due to the interference of a pituitary mass with dopaminergic inhibition of prolactin secretion.
[2]
Reference
