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Details for phenotype: Acromegaly due to pituitary adenoma
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EndoNet ID: ENP00507
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Name
Acromegaly due to pituitary adenoma
General information
This phenotype is pathologic
Acromegaly is a disorder of disproportionate skeletal, tissue, and organ growth.
[1]
Links to other resources
GO
regulation of growth hormone secretion
OMIM
102200
Medline Plus
000321
MeSH term
D000172
Disease database
114
Phenotype triggers
more activity (high ligand concentration, overexpression) of
growth hormone receptor
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in
pituitary_gland_of_diencephalon
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Dysregulated growth hormone hypersecretion is usually caused by a GH-secreting pituitary adenoma and leads to acromegaly.
[1]
Reference
