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Details for phenotype: gastro-intestinal system smooth muscle contraction

EndoNet ID: ENP00516

Name

gastro-intestinal system smooth muscle contraction

General information

This phenotype is not pathologic

Links to other resources

GO
MeSH term 68009119

Phenotype triggers

  • normal activity of 5-HT-2B
    in stomach
    • 5-HT 2B receptors are found peripherally in the stomach fundus and contraction of the rat stomach fundus via these receptors has been elicited. [1]
  • normal activity of CCK-1
    in gallbladder
    • In human gallbladder the CCK-induced contraction of the smooth muscle is mediate through the CCK1 receptor. [2]
    • In humans strong evidence suggests CCK1R activation is involved in the regulation of numerous physiological processes, including gallbladder contraction. [3]
Reference