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Statistic
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Details for phenotype: regulation of endothelial cell differentiation
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EndoNet ID: ENP00556
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Name
regulation of endothelial cell differentiation
General information
This phenotype is not pathologic
Links to other resources
GO
regulation of endothelial cell differentiation
MeSH term
68002454
Phenotype triggers
normal activity of
Sphingosine 1-phosphate receptor 1
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in
continuous_vascular_endothelial_cell_of_blood_vessels_and_lymphatics
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S1PR1 is the receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. This inducible epithelial cell G-protein-coupled receptor may be involved in the processes that regulate the differentiation of endothelial cells.
[1]
normal activity of
Vascular endothelial growth factor receptor 2
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in
sinusoidal_endothelial_cell
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VEGFR2 signaling is required for capillary tube formation, it regulates the differentiation of endothelial cells into capillary tubes.
[2]
Reference
