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Statistic
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Details for phenotype: preeclampsia
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EndoNet ID: ENP00557
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Name
preeclampsia
General information
This phenotype is pathologic
Preeclampsia is a pregancy disorder that is characterized by hypertension and proteinuria occurring after the 20th week of gestation.
[1]
Links to other resources
GO
regulation of blood pressure
Medline Plus
000898
MeSH term
D011225
Disease database
10494
Phenotype triggers
more activity (high ligand concentration, overexpression) of
Vascular endothelial growth factor receptor 1
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in
placenta
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Increased levels of soluble VEGFR1 variant (sFlt1) in the placenta and reduced levels of PlGF predict the subsequent development of preeclampsia.
[2]
Reference
