Status
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Details for phenotype: negative regulation of osteoclast differentiation

EndoNet ID: ENP00562

Name

negative regulation of osteoclast differentiation

General information

This phenotype is not pathologic

Links to other resources

GO
MeSH term 68010010

Phenotype triggers

  • normal activity of Tumor necrosis factor receptor superfamily member 11B
    in osteoblast
    • Tumor necrosis factor receptor superfamily member 11B specifically inhibits osteoclastogenesis in a dose-dependent manner elicited through three distinct signaling patways stimulated by 1alpha,25-dihydroxy vitamin D3, parathyroid hormone, and interleukin-11. [1]
Reference