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Details for phenotype: detection of mechanical stimulus

EndoNet ID: ENP00575

Name

detection of mechanical stimulus

General information

This phenotype is not pathologic

Links to other resources

GO
MeSH term 68012677

Phenotype triggers

  • normal activity of Transient receptor potential cation channel subfamily V member 1
    in urinary_bladder
    • VR1 has a role in normal bladder function and sensing of bladder distension, particularly via the detection of mechanical stimuli by the urothelium. [1]
  • normal activity of ER-beta
    in osteocyte
    • Membrane associated estrogen receptors are essential for the transduction of mecahnical forces into intracellular survival signaling in osteocytes and osteoblast, independent of ligand binding. [2]
Reference