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Details for phenotype: positive regulation of lymphocyte apoptosis

EndoNet ID: ENP00583

Name

positive regulation of lymphocyte apoptosis

General information

This phenotype is not pathologic

Links to other resources

GO
MeSH term 68051017

Phenotype triggers

  • normal activity of TNFRSF25
    in spleen
    • TNFRSF25 is up-regulated by alternative splicing in response to lymphocyte activation, this means that it is ideally placed to play a role in controlling lymphocyte proliferation. [1]
    • The restricted expression of TNFRSF25 suggests that like Fas receptor it may play a role in immune development and function. [1]
  • normal activity of TNFRSF25
    in lymphocyte
    • The potential importance of TNFRSF25 in lymphocyte apoptosis is reflected by its restricted pattern of expression, predominantly on lymphocytes. [1]
  • normal activity of TNFRSF25
    in colon
    • TNFRSF25 is up-regulated by alternative splicing in response to lymphocyte activation, this means that it is ideally placed to play a role in controlling lymphocyte proliferation. [1]
    • The restricted expression of TNFRSF25 suggests that like Fas receptor it may play a role in immune development and function. [1]
    • TNFRSF25 was detected in lymphocyte-rich tissues such as the thymus, colon, intestine, and spleen. [2]
Reference