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Statistic
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Details for phenotype: negative regulation of angiogenesis
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EndoNet ID: ENP00608
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Name
negative regulation of angiogenesis
General information
This phenotype is not pathologic
Links to other resources
GO
negative regulation of angiogenesis
MeSH term
68020533
Phenotype triggers
normal activity of
thrombospondin receptor
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in
continuous_vascular_endothelial_cell_of_blood_vessels_and_lymphatics
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CD36 mediates the antiangiogenic signal of TSP-1.
[1]
normal activity of
beta-1 adrenoreceptor
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in
mast_cell
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Blockade of β1- and β2-adrenoceptors increases the number of mast cells, promoting proliferation and differentiation of fibroblasts. Additionally, blockade of β1- and β2-adrenoceptors increases the migration of mast cells, resulting in increased angiogenesis.
[2]
normal activity of
beta-2 adrenoreceptor
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in
mast_cell
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Blockade of β1- and β2-adrenoceptors increases the number of mast cells, promoting proliferation and differentiation of fibroblasts. Additionally, blockade of β1- and β2-adrenoceptors increases the migration of mast cells, resulting in increased angiogenesis.
[2]
Reference
