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Statistic
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Details for phenotype: colonocyte differentiation
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EndoNet ID: ENP00673
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Name
colonocyte differentiation
General information
This phenotype is not pathologic
Links to other resources
Phenotype triggers
normal activity of
CaSR
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in
colon
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The CaSR plays an important role in the proliferation and differentiation of colonocytes.
[1]
The CaSR promotes the expression of E-cadherin and suppresses the activation of ß-catenin/ TCF factor, therby regulating the differentiation of colonic epithelial cells.
[2]
Reference