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Statistic
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Details for phenotype: termination of excitatory nerve signals
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EndoNet ID: ENP00675
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Name
termination of excitatory nerve signals
General information
This phenotype is not pathologic
Links to other resources
Phenotype triggers
normal activity of
GLAST
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in
bergmann_glia
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GLAST regulates the uptake of glutamate, important for the termination of excitatory signals and the maintenance of non-toxic concentrations.
[1]
normal activity of
GLT1
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in
astrocyte
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The astrocyte glutamate transporter GLT1 is responsible for significant portions of glutamate transport from the synaptic cleft, therby regulating synaptic transmission and preventing exitotoxicity.
[2]
Reference
