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Statistic
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Details for phenotype: negative regulation of osteoclast proliferation
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EndoNet ID: ENP00713
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Name
negative regulation of osteoclast proliferation
General information
This phenotype is not pathologic
Links to other resources
GO
negative regulation of osteoclast proliferation
Phenotype triggers
normal activity of
ER-alpha
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in
osteoclast
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Estrognes attenuate osteclastogenesis and life span and stimulate osteoclast apoptosis via cell-autonomous actions mediated by DNA binding-independent action of ER alpha.
[1]
normal activity of
ER-beta
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in
osteoclast
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Estrogen inhibits osteoclastogenesis.
[2]
Reference
