Status
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Details for phenotype: polycystic ovary syndrome

EndoNet ID: ENP00719

Name

polycystic ovary syndrome

General information

This phenotype is not pathologic

Links to other resources

OMIM 184700
MeSH term D011085

Phenotype triggers

  • more activity (high ligand concentration, overexpression) of AR
    in theca_cell
    • Hyperandrogenemia arises from ovarian or adrenal dysfunction or tumors, disturbed peripheral metabolism of androgen precursors or exogenous androgenic medications. [1]
    • Polycystic ovary syndrome, a polymorphic hyperandrogenic disorder, is often assiciated with insulin resistance and acanthosis nigricans in obese women, a combination termed Hair-An syndrome. [2]
Reference