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Details for receptor: CHRNA1-2

EndoNet ID: ENR00114

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Synonyms

  • Acetylcholine receptor subunit alpha
  • CHRNA1-2
  • alpha-nAChR
  • alpha nicotinic acetylcholine receptor
  • ACHRA
  • CHNRA

General information

  • Binding of acetylcholine leads to a conformational change which opens an ion-conducting channel across the plasma membrane.

Links to other resources

UniProt P02708
Ensembl ENST00000448239

Subunit information

Isoform 2

Sequence
SEHETRLVA KLFKDYSSV VRPVEDHRQ 
VVEVTVGLQ LIQLINVDE VNQIVTTNV 
RLKQGDMVD LPRPSCVTL GVPLFSHLQ 
NEQWVDYNL KWNPDDYGG VKKIHIPSE 
KIWRPDLVL YNNADGDFA IVKFTKVLL 
QYTGHITWT PPAIFKSYC EIIVTHFPF 
DEQNCSMKL GTWTYDGSV VAINPESDQ 
PDLSNFMES GEWVIKESR GWKHSVTYS 
CCPDTPYLD ITYHFVMQR LPLYFIVNV 
IIPCLLFSF LTGLVFYLP TDSGEKMTL 
SISVLLSLT VFLLVIVEL IPSTSSAVP 
LIGKYMLFT MVFVIASII ITVIVINTH 
HRSPSTHVM PNWVRKVFI DTIPNIMFF 
STMKRPSRE KQDKKIFTE DIDISDISG 
KPGPPPMGF HSPLIKHPE VKSAIEGIK 
YIAETMKSD QESNNAAAE WKYVAMVMD 
HILLGVFML VCIIGTLAV FAGRLIELN 
QQG
UniProt P02708-1

Binding hormones

  • acetylcholine

Anatomical structures with this receptor

  • skeleton_muscle

  • brain

  • heart

  • kidney

  • liver

  • lung

  • thymus

  • adrenal_medulla

Reference