Status
Please wait ...

Details for receptor: PPAR beta/delta

  • Top
  • General information
  • Subunits
    •
  • External resources
  • General information
  • Hormones
  • Anatomical structures
  • Click to access the toolbox
EndoNet ID: ENR00122

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be: 

http://endonet.bioinf.med.uni-goettingen.de/hormone/ENH00000

It is also possible to use the search of EndoNet to link to the right detail page. The URL should look like 

http://endonet.bioinf.med.uni-goettingen.de/search/ENC00000
If the search pattern is unambigious the user is directed to the corresponding detail page.

Synonyms

  • PPAR beta
  • PPAR delta
  • PPAR beta/delta

General information

  • The peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone receptor subfamily of transcription factors. [1]
  • PPARs form heterodimers with retinoid X receptors and these heterodimers regulate transcription of various genes. [2]

Links to other resources

UniProt Q03181

Subunit information

PPAR gamma

Sequence 
MEQPQEEAP EVREEEEKE EVAEAEGAP 
ELNGGPQHA LPSSSYTDL SRSSSPPSL 
LDQLQMGCD GASCGSLNM ECRVCGDKA 
SGFHYGVHA CEGCKGFFR RTIRMKLEY 
EKCERSCKI QKKNRNKCQ YCRFQKCLA 
LGMSHNAIR FGRMPEAEK RKLVAGLTA 
NEGSQYNPQ VADLKAFSK HIYNAYLKN 
FNMTKKKAR SILTGKASH TAPFVIHDI 
ETLWQAEKG LVWKQLVNG LPPYKEISV 
HVFYRCQCT TVETVRELT EFAKSIPSF 
SSLFLNDQV TLLKYGVHE AIFAMLASI 
VNKDGLLVA NGSGFVTRE FLRSLRKPF 
SDIIEPKFE FAVKFNALE LDDSDLALF 
IAAIILCGD RPGLMNVPR VEAIQDTIL 
RALEFHLQA NHPDAQYLF PKLLQKMAD 
LRQLVTEHA QMMQRIKKT ETETSLHPL 
LQEIYKDMY

Binding hormones

  • free fatty acid

Anatomical structures with this receptor

  • skeleton_muscle

    • A study with human tissues showed that PPARä was present in liver, intestine, kidney, abdominal adipose, and skeletal muscle, tissues that are all involved in aspects of lipid metabolism [3]

  • adipose_tissue

    • A study with human tissues showed that PPARä was present in liver, intestine, kidney, abdominal adipose, and skeletal muscle, tissues that are all involved in aspects of lipid metabolism [3]

  • kidney

    • A study with human tissues showed that PPARä was present in liver, intestine, kidney, abdominal adipose, and skeletal muscle, tissues that are all involved in aspects of lipid metabolism [3]

  • small_intestine

    • A study with human tissues showed that PPARä was present in liver, intestine, kidney, abdominal adipose, and skeletal muscle, tissues that are all involved in aspects of lipid metabolism [3]

  • large_intestine

    • A study with human tissues showed that PPARä was present in liver, intestine, kidney, abdominal adipose, and skeletal muscle, tissues that are all involved in aspects of lipid metabolism [3]

  • liver

    • A study with human tissues showed that PPARä was present in liver, intestine, kidney, abdominal adipose, and skeletal muscle, tissues that are all involved in aspects of lipid metabolism [3]

  • skin

    • Of the three isotypes, PPAR/ has the broadest expression pattern, and the levels of expression in certain tissues depend on the extent of cell proliferation and differentiation. Important functions have been assigned to this isotype in the skin, gut, placenta, skeletal muscle, adipose tissue, and brain [4]

  • placenta

    • Of the three isotypes, PPAR/ has the broadest expression pattern, and the levels of expression in certain tissues depend on the extent of cell proliferation and differentiation. Important functions have been assigned to this isotype in the skin, gut, placenta, skeletal muscle, adipose tissue, and brain [4]

  • brain

    • Of the three isotypes, PPAR/ has the broadest expression pattern, and the levels of expression in certain tissues depend on the extent of cell proliferation and differentiation. Important functions have been assigned to this isotype in the skin, gut, placenta, skeletal muscle, adipose tissue, and brain [4]
Reference