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Details for receptor: OX40

EndoNet ID: ENR00420

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Synonyms

  • OX40
  • TNFRSF4
  • ACT35
  • TXGP1L
  • CD134
  • OX40 cell surface antigen
  • TNF receptor superfamily, member 4
  • OX40L receptor
  • TAX transcriptionally-activated glycoprotein 1 R

General information

  • Receptor for TNFSF4/OX40L/GP34. [1]
  • OX40 is an approximately 50-kD glycoprotein and is a type 1 transmembrane protein of 249 amino acids, with a 49 amino acid cytoplasmic tail and a 186 amino acid extracellular region. [2]

Links to other resources

UniProt P43489
Ensembl ENST00000453580

Binding hormones

  • OX40L
    • OX40 is a receptor for OX40-ligand. [1]

Anatomical structures with this receptor

  • T-lymphocyte

    • OX40 has since been characterized in mouse and human, where its expression is also restricted to activated T cells [3]
Reference