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Details for receptor: HVEM

EndoNet ID: ENR00425

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Synonyms

  • HVEM
  • TNFRSF14
  • TNF receptor superfamily member 14
  • herpesvirus entry mediator A
  • tumor necrosis factor receptor-like 2
  • TR2
  • HVEA

General information

  • Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells. [1]

Links to other resources

UniProt Q92956
Ensembl ENST00000451778

Binding hormones

  • LIGHT
    • LIGHT is a tumor necrosis factor (TNF) ligand superfamily member, which binds to the herpesvirus entry mediator (HveA) [2]

Anatomical structures with this receptor

    Reference