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Details for receptor: DR4

EndoNet ID: ENR00584

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Synonyms

  • APO2
  • DR4
  • TNFRSF10A
  • TNF receptor superfamily member 10a
  • TRAILR-1
  • TRAILR1
  • CD261
  • death receptor 4
  • TNF-related apoptosis-inducing ligand receptor 1
  • TRAIL receptor 1
  • CD261 antigen

General information

  • DR4 triggers apoptosis. [1]

Links to other resources

UniProt O00220
Ensembl ENST00000221132

Subunit information

TNFRSF10A

Sequence
ASGTEAAAA TPSKVWGSS AGRIEPRGG 
GRGALPTSM GQHGPSARA RAGRAPGPR 
PAREASPRL RVHKTFKFV VVGVLLQVV 
PSSAATIKL HDQSIGTQQ WEHSPLGEL 
CPPGSHRSE HPGACNRCT EGVGYTNAS 
NNLFACLPC TACKSDEEE RSPCTTTRN 
TACQCKPGT FRNDNSAEM CRKCSRGCP 
RGMVKVKDC TPWSDIECV HKESGNGHN 
IWVILVVTL VVPLLLVAV LIVCCCIGS 
GCGGDPKCM DRVCFWRLG LLRGPGAED 
NAHNEILSN ADSLSTFVS EQQMESQEP 
ADLTGVTVQ SPGEAQCLL GPAEAEGSQ 
RRRLLVPAN GADPTETLM LFFDKFANI 
VPFDSWDQL MRQLDLTKN EIDVVRAGT 
AGPGDALYA MLMKWVNKT GRNASIHTL 
LDALERMEE RHAKEKIQD LLVDSGKFI 
YLEDGTGSA VSLE

Binding hormones

  • TNFSF10

Anatomical structures with this receptor

  • spleen

  • peripheral blood leukocytes

  • small_intestine

  • thymus

Reference