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Details for receptor: DcR2

EndoNet ID: ENR00585

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Synonyms

  • DcR2
  • TNFRSF10D
  • TNF receptor superfamily member 10D
  • decoy receptor 2
  • TNF-related apoptosis-inducing ligand receptor 4
  • TRAIL receptor 4
  • TRAIL-R4
  • TRAIL receptor with a truncated death domain
  • CD264 antigen
  • TRAILR4
  • TRUNDD

General information

  • Receptor for the cytotoxic ligand TRAIL (TNFSF10). Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. [1]

Links to other resources

UniProt Q9UBN6
Ensembl ENST00000312584

Subunit information

Tumor necrosis factor receptor superfamily member

Sequence
ATIPRQDEV PQQTVAPQQ QRRSLKEEE 
CPAGSHRSE YTGACNPCT EGVDYTIAS 
NNLPSCLLC TVCKSGQTN KSSCTTTRD 
TVCQCEKGS FQDKNSPEM CRTCRTGCP 
RGMVKVSNC TPRSDIKCK NESAASSTG 
KTPAAEETV TTILGMLAS PYHYLIIIV 
VLVIILAVV VVGFSCRKK FISYLKGIC 
SGGGGGPER VHRVLFRRR SCPSRVPGA 
EDNARNETL SNRYLQPTQ VSEQEIQGQ 
ELAELTGVT VESPEEPQR LLEQAEAEG 
CQRRRLLVP VNDADSADI STLLDASAT 
LEEGHAKET IQDQLVGSE KLFYEEDEA 
GSATSCL

Binding hormones

  • TNFSF10

Anatomical structures with this receptor

    Reference