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Details for receptor: DcR1

EndoNet ID: ENR00586

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  • DcR1
  • LIT
  • TRID
  • CD263
  • TNF receptor superfamily member 10c
  • decoy receptor 1
  • decoy TRAIL receptor without death domain
  • TNF-related apoptosis-inducing ligand receptor 3
  • TRAIL receptor 3
  • TRAIL-R3
  • trail receptor without an intracellular domain
  • lymphocyte inhibitor of TRAIL
  • antagonist decoy receptor for TRAIL/Apo-2L
  • CD263 antigen

General information

  • GPI-anchored membrane receptor without cytoplasmic death domain.
  • Receptor for the cytotoxic ligand TRAIL (TNFSF10). Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand. [1]

Links to other resources

UniProt O14798
Ensembl ENST00000397703

Binding hormones

  • TNFSF10

Anatomical structures with this receptor