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Details for receptor: IL-15R alpha

EndoNet ID: ENR00621

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Synonyms

  • IL-15R alpha
  • IL-15R
  • interleukin-15 receptor alpha
  • IL15R
  • interleukin-15 receptor
  • IL-15Ralpha
  • IL-15 receptor alpha

General information

  • The interleukin-15 receptor IL15R is a heterotrimer of IL15RA, IL2RB and IL2RG, IL15RA also self-associates. [1]

Links to other resources

UniProt Q13261
Ensembl ENST00000453922

Subunit information

interleukin-2 receptor subunit beta (1 times)

Sequence
AVNGTSQFT CFYNSRANI SCVWSQDGA 
LQDTSCQVH AWPDRRRWN QTCELLPVS 
QASWACNLI LGAPDSQKL TTVDIVTLR 
VLCREGVRW RVMAIQDFK PFENLRLMA 
PISLQVVHV ETHRCNISW EISQASHYF 
ERHLEFEAR TLSPGHTWE EAPLLTLKQ 
KQEWICLET LTPDTQYEF QVRVKPLQG 
EFTTWSPWS QPLAFRTKP AALGKDTIP 
WLGHLLVGL SGAFGFIIL VYLLINCRN 
TGPWLKKVL KCNTPDPSK FFSQLSSEH 
GGDVQKWLS SPFPSSSFS PGGLAPEIS 
PLEVLERDK VTQLLLQQD KVPEPASLS 
SNHSLTSCF TNQGYFFFH LPDALEIEA 
CQVYFTYDP YSEEDPDEG VAGAPTGSS 
PQPLQPLSG EDDAYCTFP SRDDLLLFS 
PSLLGGPSP PSTAPGGSG AGEERMPPS 
LQERVPRDW DPQPLGPPT PGVPDLVDF 
QPPPELVLR EAGEEVPDA GPREGVSFP 
WSRPPGQGE FRALNARLP LNTDAYLSL 
QELQGQDPT HLV
UniProt P14784

IL-15R-alpha chain, isoform 1 (1 times)

Sequence
ITCPPPMSV EHADIWVKS YSLYSRERY 
ICNSGFKRK AGTSSLTEC VLNKATNVA 
HWTTPSLKC IRDPALVHQ RPAPPSTVT 
TAGVTPQPE SLSPSGKEP AASSPSSNN 
TAATTAAIV PGSQLMPSK SPSTGTTEI 
SSHESSHGT PSQTTAKNW ELTASASHQ 
PPGVYPQGH SDTTVAIST STVLLCGLS 
AVSLLACYL KSRQTPPLA SVEMEAMEA 
LPVTWGTSS RDEDLENCS HHL
UniProt Q13261-1

Il-2R gamma chain (1 times)

Sequence
LNTTILTPN GNEDTTADF FLTTMPTDS 
LSVSTLPLP EVQCFVFNV EYMNCTWNS 
SSEPQPTNL TLHYWYKNS DNDKVQKCS 
HYLFSEEIT SGCQLQKKE IHLYQTFVV 
QLQDPREPR RQATQMLKL QNLVIPWAP 
ENLTLHKLS ESQLELNWN NRFLNHCLE 
HLVQYRTDW DHSWTEQSV DYRHKFSLP 
SVDGQKRYT FRVRSRFNP LCGSAQHWS 
EWSHPIHWG SNTSKENPF LFALEAVVI 
SVGSMGLII SLLCVYFWL ERTMPRIPT 
LKNLEDLVT EYHGNFSAW SGVSKGLAE 
SLQPDYSER LCLVSEIPP KGGALGEGP 
GASPCNQHS PYWAPPCYT LKPET
UniProt P31785

Binding hormones

  • IL-15
    • IL-15 isoform 6, isoform 7, isoform 8 and isoform 9 do not bind IL-15. [1]

Anatomical structures with this receptor

  • monocyte

  • macrophage

  • keratinocyte

  • fibroblast

  • nerve

  • epithelial_cell

Reference