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Details for receptor: CCR-2

EndoNet ID: ENR00687

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Synonyms

  • CCR2B
  • CCR-2
  • monocyte chemoattractant protein 1 receptor
  • CCR2
  • CC-CKR-2
  • C-C CKR-2
  • MCP-1-R
  • C-C chemokine receptor type 2

General information

  • Monocyte expression of the MCP-1 receptor, CCR2, is inhibited by interferon-gamma. [1]
  • Receptor for the MCP-1, MCP-3 and MCP-4 chemokines. [2]

Links to other resources

UniProt P41597
Ensembl ENST00000445132

Subunit information

isoform A

Sequence
MLSTSRSRF IRNTNESGE EVTTFFDYD 
YGAPCHKFD VKQIGAQLL PPLYSLVFI 
FGFVGNMLV VLILINCKK LKCLTDIYL 
LNLAISDLL FLITLPLWA HSAANEWVF 
GNAMCKLFT GLYHIGYFG GIFFIILLT 
IDRYLAIVH AVFALKART VTFGVVTSV 
ITWLVAVFA SVPGIIFTK CQKEDSVYV 
CGPYFPRGW NNFHTIMRN ILGLVLPLL 
IMVICYSGI LKTLLRCRN EKKRHRAVR 
VIFTIMIVY FLFWTPYNI VILLNTFQE 
FFGLSNCES TSQLDQATQ VTETLGMTH 
CCINPIIYA FVGEKFRSL FHIALGCRI 
APLQKPVCG GPGVRPGKN VKVTTQGLL 
DGRGKGKSI GRAPEASLQ DKEGA
UniProt P41597-1

Binding hormones

  • MCP-3
  • MCP-4
  • C-C motif chemokine 2

Anatomical structures with this receptor

  • monocyte

Reference