Status
Please wait ...

Details for receptor: PR B

  • Top
  • General information
  • External resources
  • General information
  • Hormones
  • Anatomical structures
  • Click to access the toolbox
EndoNet ID: ENR00694

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be: 

http://endonet.bioinf.med.uni-goettingen.de/hormone/ENH00000

It is also possible to use the search of EndoNet to link to the right detail page. The URL should look like 

http://endonet.bioinf.med.uni-goettingen.de/search/ENC00000
If the search pattern is unambigious the user is directed to the corresponding detail page.

Synonyms

  • progesterone receptor B
  • NR3C3b
  • PR B

General information

  • PRB was detected in eccrine sweat glands, sebaceous glands, epidermis and outer root sheath of hair follicles. [1]
  • Progesterone receptors A and B differentially modulate corticotropin-releasing hormone. [2]
  • An increase in CRH promoter activity was observed with overexpressed PR-B. [2]

Links to other resources

UniProt P06401-1
Ensembl ENST00000325455

Binding hormones

  • progesterone
    • In vertebrates and humans, the biological activity of progesterone is mediated by two progesterone receptor proteins PR-A and PR-B. [3]

Anatomical structures with this receptor

  • eccrine_sweat_glands

  • sebaceous_glands

    Induced phenotypes

    • sebaceous gland development
      • Progesterone could increase the size of sebaceous glands in spayed rats. [4]
      • But this hormone is not responsible for maintaining sebaceous gland secretion. [5]

  • epidermis

  • hair_follicle

Reference