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Details for receptor: H3

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EndoNet ID: ENR00725

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be: 

http://endonet.bioinf.med.uni-goettingen.de/hormone/ENH00000

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http://endonet.bioinf.med.uni-goettingen.de/search/ENC00000
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Synonyms

  • H3
  • histamine H3 receptor
  • G-protein coupled receptor 97
  • HH3R

General information

  • Expression in histaminergic neurons, eosinophils, dendritic cells, monocytes, low expression in peripheral tissues. [1]
  • HR3 has initially been identifi ed in the central and peripheral nervous system as presynaptic receptors controlling the release of histamine and other neurotransmitters (dopamine, serotonine, noradrenaline, gamma-aminobutyric acid and acetylocholine). [1]
  • Activated intracellular signals: enhanced Ca+2, MAP kinase, inhibition of cAMP. [1]

Links to other resources

UniProt Q9Y5N1
Ensembl ENST00000456442

Binding hormones

  • histamine

Anatomical structures with this receptor

  • monocyte

  • dendritic_cell_in_lymphoid_tissues

  • eosinophil_granulocyte

Reference