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Details for receptor: NK-3R

EndoNet ID: ENR00736

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Synonyms

  • tachykinin receptor 3
  • neuromedin K receptor
  • NK3
  • NK-3R
  • NKR
  • NK-3 receptor
  • neurokinin B receptor

General information

  • The neurokinin B receptor (NK3) is an element of the hypothalamic neuronal circuitry regulating blood pressure. [1]
  • Rank order of affinity of this receptor to tachykinins is: neuromedin K > substance K > substance P. [2]

Links to other resources

UniProt P29371
Ensembl ENST00000304883

Subunit information

neuromedin K receptor

Sequence
MATLPAAET WIDGGGGVG ADAVNLTAS 
LAAGAATGA VETGWLQLL DQAGNLSSS 
PSALGLPVA SPAPSQPWA NLTNQFVQP 
SWRIALWSL AYGVVVAVA VLGNLIVIW 
IILAHKRMR TVTNYFLVN LAFSDASMA 
AFNTLVNFI YALHSEWYF GANYCRFQN 
FFPITAVFA SIYSMTAIA VDRYMAIID 
PLKPRLSAT ATKIVIGSI WILAFLLAF 
PQCLYSKTK VMPGRTLCF VQWPEGPKQ 
HFTYHIIVI ILVYCFPLL IMGITYTIV 
GITLWGGEI PGDTCDKYH EQLKAKRKV 
VKMMIIVVM TFAICWLPY HIYFILTAI 
YQQLNRWKY IQQVYLASF WLAMSSTMY 
NPIIYCCLN KRFRAGFKR AFRWCPFIK 
VSSYDELEL KTTRFHPNR QSSMYTVTR 
MESMTVVFD PNDADTTRS SRKKRATPR 
DPSFNGCSR RNSKSASAT SSFISSPYT 
SVDEYS

Binding hormones

  • SP
  • neurokinin A
  • neuromedin-K

Anatomical structures with this receptor

    Reference