Please wait ...

Details for receptor: H1

EndoNet ID: ENR00748

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be:

It is also possible to use the search of EndoNet to link to the right detail page. The URL should look like
If the search pattern is unambigious the user is directed to the corresponding detail page.


  • histamine receptor 1
  • H1

General information

  • Expression in nerve cells, airway and vascular smooth muscles, hepatocytes, chondrocytes, endothelial cells, epithelial cells, neutrophils, eosinophils, monocytes, dendritic cells(DCs), T and B cells. [1]
  • Activated intracellular signals: Ca+2, cGMP, phospholipase D, phospholipase A2, NF-kB [1]

Links to other resources

UniProt P35367
Ensembl ENST00000438284

Binding hormones

  • histamine
    • Histamine acting through the H1 receptor is known to be a potent positive regulator of Il-6. [2]

Anatomical structures with this receptor

  • nerve

  • hepatocyte

  • chondrocyte

  • continuous_vascular_endothelial_cell_of_blood_vessels_and_lymphatics

  • epithelial_cell

  • neutrophil_granulocyte

  • dendritic_cell_in_lymphoid_tissues

  • B-lymphocyte

  • T-lymphocyte