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Details for receptor: H1

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EndoNet ID: ENR00748

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be: 

http://endonet.bioinf.med.uni-goettingen.de/hormone/ENH00000

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http://endonet.bioinf.med.uni-goettingen.de/search/ENC00000
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Synonyms

  • histamine receptor 1
  • H1

General information

  • Expression in nerve cells, airway and vascular smooth muscles, hepatocytes, chondrocytes, endothelial cells, epithelial cells, neutrophils, eosinophils, monocytes, dendritic cells(DCs), T and B cells. [1]
  • Activated intracellular signals: Ca+2, cGMP, phospholipase D, phospholipase A2, NF-kB [1]

Links to other resources

UniProt P35367
Ensembl ENST00000438284

Binding hormones

  • histamine
    • Histamine acting through the H1 receptor is known to be a potent positive regulator of Il-6. [2]

Anatomical structures with this receptor

  • nerve

  • hepatocyte

  • chondrocyte

  • continuous_vascular_endothelial_cell_of_blood_vessels_and_lymphatics

  • epithelial_cell

  • neutrophil_granulocyte

  • dendritic_cell_in_lymphoid_tissues

  • B-lymphocyte

  • T-lymphocyte

Reference