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Details for receptor: follitropin receptor

EndoNet ID: ENR00788

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Synonyms

  • FSH-R
  • follitropin receptor
  • follicle stimulating hormone receptor

General information

  • It is found only in the gonads. [1]
  • A member of the family of G protein-coupled receptors. [1]

Links to other resources

UniProt P23945
Ensembl ENST00000454032

Binding hormones

  • FSH
    (trough: blood
    )

Anatomical structures with this receptor

  • Sertoli_cell

    Influences

    • inhibin B
  • granulosa_cell

    Influences

    • positive estradiol

    Induced phenotypes

    • granulosa cell differentiation
      • Follicle-stimuating hormone has a central role in ovarian folliculogenesis, particularly in regulating granulosa cell differentiation, it enhances expression of steroidogenic enzymes such as cytochrome P450 side-chain cleavage and P450 aromatase (these actions are importantly modulated by various growth factors, acting in paracrine or autocrine way). [2]
    • ovarian follicle development
      • Follicle-stimuating hormone has a central role in ovarian folliculogenesis. [2]
  • cell_of_adrenal_gland_zona_glomerulosa

    Influences

    • progesterone
Reference