Status
Please wait ...

Details for receptor: 5-HT-2C

  • Top
  • General information
  • External resources
  • General information
  • Hormones
  • Anatomical structures
  • Click to access the toolbox
EndoNet ID: ENR00797

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be: 

http://endonet.bioinf.med.uni-goettingen.de/hormone/ENH00000

It is also possible to use the search of EndoNet to link to the right detail page. The URL should look like 

http://endonet.bioinf.med.uni-goettingen.de/search/ENC00000
If the search pattern is unambigious the user is directed to the corresponding detail page.

Synonyms

  • serotonin receptor 2C
  • 5HT-1C
  • 5-hydroxytryptamine receptor 2C
  • 5-HT-2C

General information

Links to other resources

UniProt P28335
Ensembl ENST00000371951

Binding hormones

  • serotonin

Anatomical structures with this receptor

  • hippocampus

  • substantia_nigra

    Influences

    • positive GABA
      • The selective activation of 5-HT2C receptors stimulates non-DA neurons in the substantia nigra pars reticulata (SNr) and mediate an increase in GABA extracellular levels in the SNr. [1]
    • The location of 5-HT-2C recpetors is on postsynaptic sites of the substantia nigra. [2]

  • cerebral_cortex

  • corpus_striatum

    Influences

    • dopamine
      • Stimulate 5-HT-2C receptors localized within the striatum have an inhibitory controll of the dopamine release in the nitrostriatal pathway. [3]

  • frontal_lobe

    Influences

    • positive acetylcholine
      • Acitvation of the 5-HT2 receptors stimulate the release of ACh in the prefontal cortex. [4]
Reference