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Details for receptor: KOR

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EndoNet ID: ENR00820

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For an hormone that would be: 

http://endonet.bioinf.med.uni-goettingen.de/hormone/ENH00000

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Synonyms

  • kappa-opioid receptor
  • kappa-type opioid receptor
  • KOR
  • KOR-1
  • OPRK1
  • OPRK

General information

  • Dynorphin A (Dyn A), and dynorphin B (Dyn B) are endogenous opioid peptides that activate the kappa-opioid receptor (KOR). [1]

Links to other resources

UniProt P41145
Ensembl ENST00000396798

Subunit information

Sequence 
MESPIQIFR GEPGPTCAP SACLPPNSS 
AWFPGWAEP DSNGSAGSE DAQLEPAHI 
SPAIPVIIT AVYSVVFVV GLVGNSLVM 
FVIIRYTKM KTATNIYIF NLALADALV 
TTTMPFQST VYLMNSWPF GDVLCKIVI 
SIDYYNMFT SIFTLTMMS VDRYIAVCH 
PVKALDFRT PLKAKIINI CIWLLSSSV 
GISAIVLGG TKVREDVDV IECSLQFPD 
DDYSWWDLF MKICVFIFA FVIPVLIII 
VCYTLMILR LKSVRLLSG SREKDRNLR 
RITRLVLVV VAVFVVCWT PIHIFILVE 
ALGSTSHST AALSSYYFC IALGYTNSS 
LNPILYAFL DENFKRCFR DFCFPLKMR 
MERQSTSRV RNTVQDPAY LRDIDGMNK 
PV

Binding hormones

  • dynorphin A
    • Dyn A and Dyn B bound to three subtypes of opioid receptors showing higher affinity for hKOR than for hMOR and hDOR. [1]
  • dynorphin B
  • big dynorphin
  • Alpha-neoendorphin
    • Alpha-neoendorphin is a potent full agonist of the kappa-opioid receptor. [2]

Anatomical structures with this receptor

    Reference