Please wait ...

Details for receptor: TGF-beta type I receptor

EndoNet ID: ENR00834

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be:

It is also possible to use the search of EndoNet to link to the right detail page. The URL should look like
If the search pattern is unambigious the user is directed to the corresponding detail page.


  • TGFbetaR-I
  • TGFR-1
  • TGF-beta type I receptor
  • serine/threonine-protein kinase receptor R4
  • SKR4
  • activin receptor-like kinase 5
  • ALK-5

General information

  • TGF beta type I and II receptors are expressed by endometrial cells and the syncytiotrophoblast of term placenta. [1]
  • Osteoblasts expresses mRNA transcripts of TGF-beta1, TGF-beta2, TGF-beta 3, TGF-beta type I and type II receptors. [2]

Links to other resources

UniProt P36897
Ensembl ENST00000374994

Binding hormones

    Anatomical structures with this receptor

    • isocortex

    • osteoblast

    • cell_of_endometrium_of_uterus

    • placenta

    • propria_mucosa_of_bronchus


      • positive PGE2
        • In pulmonary fibroblasts, TGF-beta1 stimulates matrix synthesis while inducing COX expression and PGE2 production. [3]
    • lipocyte_of_liver