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Details for receptor: IL-18R1

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EndoNet ID: ENR00839

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For an hormone that would be: 

http://endonet.bioinf.med.uni-goettingen.de/hormone/ENH00000

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Synonyms

  • IL18R1
  • IL-1Rrp
  • IL1 receptor-related protein
  • interleukin-18 receptor 1
  • IL-18Ralpha
  • IL-18R1

General information

  • IL-12 enhances IL-1Rrp mRNA expression in B and T cells. [1]
  • Receptor for interleukin 18, does not bind IL-1A or IL-1B. [2]
  • IFN-alpha and IL-12 induce IL-1Rrp, AcPL, IL-12R-beta2, and MyD88 gene expression in resting NK cells. [1]

Links to other resources

UniProt Q13478
Ensembl ENST00000410040

Subunit information

Sequence 
AESCTSRPH ITVVEGEPF YLKHCSCSL 
AHEIETTTK SWYKSSGSQ EHVELNPRS 
SSRIALHDC VLEFWPVEL NDTGSYFFQ 
MKNYTQKWK LNVIRRNKH SCFTERQVT 
SKIVEVKKF FQITCENSY YQTLVNSTS 
LYKNCKKLL LENNKNPTI KKNAEFEDQ 
GYYSCVHFL HHNGKLFNI TKTFNITIV 
EDRSNIVPV LLGPKLNHV AVELGKNVR 
LNCSALLNE EDVIYWMFG EENGSDPNI 
HEEKEMRIM TPEGKWHAS KVLRIENIG 
ESNLNVLYN CTVASTGGT DTKSFILVR 
KADMADIPG HVFTRGMII AVLILVAVV 
CLVTVCVIY RVDLVLFYR HLTRRDETL 
TDGKTYDAF VSYLKECRP ENGEEHTFA 
VEILPRVLE KHFGYKLCI FERDVVPGG 
AVVDEIHSL IEKSRRLII VLSKSYMSN 
EVRYELESG LHEALVERK IKIILIEFT 
PVTDFTFLP QSLKLLKSH RVLKWKADK 
SLSYNSRFW KNLLYLMPA KTVKPGRDE 
PEVLPVLSE S

Binding hormones

  • IL-18

Anatomical structures with this receptor

  • lung

  • spleen

  • thymus

  • prostate

  • small_intestine

  • colon

  • placenta

  • heart

  • leukocyte

  • T-lymphocyte

  • helper_T_cell_Th1

  • killer_cell

    Influences

    • positive IFN-gamma

  • B-lymphocyte

Reference