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Details for receptor: GFR-alpha-1

EndoNet ID: ENR00872

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Synonyms

  • GFR-alpha-1
  • GDNF family receptor alpha-1
  • GDNF receptor alpha
  • GDNFR-alpha
  • TGF-beta-related neurotrophic factor receptor 1
  • RET ligand 1
  • GFRA1
  • GDNFRA
  • GFR alpha 1

General information

  • GDNF receptor alpha-1 (GFR alpha 1) is highly selective for GDNF versus artemin. [1]

Links to other resources

UniProt P56159
Ensembl ENST00000439649

Subunit information

isoform 1

Sequence
DRLDCVKAS DQCLKEQSC STKYRTLRQ 
CVAGKETNF SLASGLEAK DECRSAMEA 
LKQKSLYNC RCKRGMKKE KNCLRIYWS 
MYQSLQGND LLEDSPYEP VNSRLSDIF 
RVVPFISDV FQQVEHIPK GNNCLDAAK 
ACNLDDICK KYRSAYITP CTTSVSNDV 
CNRRKCHKA LRQFFDKVP AKHSYGMLF 
CSCRDIACT ERRRQTIVP VCSYEEREK 
PNCLNLQDS CKTNYICRS RLADFFTNC 
QPESRSVSS CLKENYADC LLAYSGLIG 
TVMTPNYID SSSLSVAPW CDCSNSGND 
LEECLKFLN FFKDNTCLK NAIQAFGNG 
SDVTVWQPA FPVQTTTAT TTTALRVKN 
KPLGPAGSE NEIPTHVLP PCANLQAQK 
LKSNVSGNT HLCISNGNY EKEGLGASS
UniProt P56159-1

Binding hormones

  • ART
  • neurturin
  • GDNF

Anatomical structures with this receptor

    Reference