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Details for receptor: sortilin

EndoNet ID: ENR00904

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Synonyms

  • sortilin
  • 100 kDa NT receptor
  • glycoprotein 95
  • GP95
  • neurotensin receptor 3
  • NT3
  • NTR-3

General information

  • Binds the receptor-associated protein (RAP). May be involved in endosomal protein sorting. Acts as a receptor for neurotensin. [1]

Links to other resources

UniProt Q99523
Ensembl ENST00000256637

Binding hormones

  • NT

Anatomical structures with this receptor

  • neuron

    Induced phenotypes

    • migration of microglia
      • NTR3 may control proliferation of human cancer cells, migration of human microglia and proNGF-induced neuronal cell death. [2]
Reference