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Details for receptor: PAR1

EndoNet ID: ENR00918

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  • PAR1

General information

Links to other resources

UniProt P25116
Ensembl ENST00000396233

Binding hormones

  • elastase-2
    • In this study, we provide evidence that leukocyte elastase perform its biological activity through PAR-1. [1]

Anatomical structures with this receptor

  • lymph_node

    Induced phenotypes

    • positive regulation of myeloid dendritic cell activation
      • PAR1-mediated activation of DCs in the lymph nodes leads to SPHK1 activation and autocrine transactivation of S1PR3. [2]